Recombinant sdAb anti-SARS-CoV-2 Spike protein S1 Rabbit Fc-fusion

Recombinant sdAb anti-SARS-CoV-2 Spike protein S1 Rabbit Fc-fusion

Cat no: N3583

Regular price € 375.00 EUR Sale

The recombinant sdAb anti-S1 (RBD of SARS-Cov-2) Rabbit Fc-fusion is a genetic fusion of the single-domain antibody anti-S1 to a Rabbit Fc domain. This bivalent tool binds the SARS-CoV-2 RBD domain of the S1 protein with high affinity and is ideally suited for ELISA and IHC staining. The fused Rabbit Fc allows for conventional secondary detections tools used in automated high-throughput-screening devices.
The minibody preserves the specificity and high affinity binding of the anti-S1 SARS-CoV-2 single-domain antibody and can neutralize infections as it efficiently competes with ACE-2 receptor binding as shown by the team of Alejandro Rojas-Fernandez at the Institute of Medicine from the Universidad Austral de Chile.

100 µg specific antibody, lyophilized. Albumin was added for stabilization. For reconstitution add 100 µl H2O to get a 1 mg/ml solution in PBS. Then aliquot and store at -20°C until use.

Immunogen: full-length S1 protein from SARS-CoV-2
Specificity: RBD of S1 protein from SARS-CoV-2
Applications: IHC (10 µg/mL), ELISA (1:1000), IF (1:500)